Biopsy diagnostics

Department of Pathologic Anatomy, Autopsy Course and Forensic Pathology

Responsible for implementation: Associate prof. Yu. Orel

Bene diagnoscitur, bene curator. This axiom of ancient medicine is relevant today as well. The spectrum of diagnostic methods, of course, incredibly
expanded. Morphological methods of investigation, which often play a major role in differentiating the diagnosis and choosing the appropriate tactics of further treatment, play an extremely important role among them. This is explained by two groups of factors: on the one hand, the possibilities of
lifetime acquisition of tissues of different organs have significantly expanded, on the other – the results of morphological studies of surgical and biopsy material have become much more informative and reliable. Although a few years ago, their scope was limited mainly to oncology and gynecology, now biopsy research is widely used in the clinic of internal medicine (including Hepatology, Nephrology), in diseases of the nervous system and many other fields of practical medicine. In addition to traditional tissue staining with hematoxylin and eosin, immunohistochemical studies are becoming routine, a commonly used method of FISH-hybridization and other techniques. Therefore, a doctor of any specialty should know the possibilities, potential advantages and disadvantages of modern methods of morphological examination of biopsy and surgical material, use them in the process of diagnostic research, as well as being able to properly capture biological material for these studies.