{"id":2149,"date":"2022-09-02T11:17:39","date_gmt":"2022-09-02T11:17:39","guid":{"rendered":"https:\/\/science.tdmu.edu.ua\/?p=2149"},"modified":"2022-09-02T11:17:39","modified_gmt":"2022-09-02T11:17:39","slug":"caffeine-metabolite-could-slow-progression-of-nearsightedness-in-children","status":"publish","type":"post","link":"https:\/\/www.tdmu.edu.ua\/science\/en\/caffeine-metabolite-could-slow-progression-of-nearsightedness-in-children\/","title":{"rendered":"Caffeine Metabolite Could Slow Progression of Nearsightedness in Children"},"content":{"rendered":"\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/nearsightedness\/symptoms-causes\/syc-20375556\">Myopia<\/a>, also known as nearsightedness, is a common vision condition in which objects far away appear blurry. Myopia occurs when the shape of your eye causes light rays to refract incorrectly, resulting in out of focus images.&nbsp;<\/p>\n\n\n\n<p class=\" eplus-wrapper\">Nearsightedness often begins in childhood and adolescence. It typically occurs first around the age of 6 and worsens into the late teenage years. Myopia tends to run in families and is also associated with a heightened risk of various eye conditions later in life, including macular degeneration, cataracts, glaucoma and retinal detachment.<\/p>\n\n\n\n<p class=\" eplus-wrapper\"><a href=\"https:\/\/www.karger.com\/Article\/Abstract\/502529\">7-Methylxanthine<\/a>&nbsp;(also known as 7-MX) is a metabolite of caffeine. It acts as an adenosine receptor (AR) antagonist and has been used to treat childhood myopia in children in Denmark since 2009. Given the success of using 7-MX as a treatment in Denmark, researchers are calling for large clinical trials to prove the safety of efficacy of 7-MX, which would allow it to be used as a treatment option for myopia.&nbsp;<\/p>\n\n\n\n<p class=\" eplus-wrapper\">It is thought that 7-MX works by inhibiting the excessive lengthening of the eye that causes myopia. In a&nbsp;<a href=\"https:\/\/www.eurekalert.org\/news-releases\/962278\">recent study<\/a>, researchers reviewed the medical records of 711 children who were treated for myopia in Denmark. Of the group of children, 624 took 7-MX tablets daily as part of their treatment.&nbsp;<\/p>\n\n\n\n<p class=\" eplus-wrapper\">The researchers found that 7-MX treatment was associated with a slower rate of worsening myopia and lengthening of the eye. They found that, without treatment, a child\u2019s axial length would increase by 1.80 mm over 6 years. With treatment, the axial length only increased by 1.63 mm. Higher doses of 7-MX seemed to be more effective and no negative effects of the treatment were reported.&nbsp;<\/p>\n\n\n\n<p class=\" eplus-wrapper\">Since this is an observational study, it cannot be determined that 7-MX was the cause of improvements in eye health. The researchers noted that \u201c 7-MX may become a valuable supplement if causality and efficacy can be confirmed in future randomized controlled trials.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Myopia, also known as nearsightedness, is a common vision condition in which objects far away appear blurry. Myopia occurs when the shape of your eye causes light rays to refract incorrectly, resulting in out of focus images.&nbsp; Nearsightedness often begins in childhood and adolescence. It typically occurs first around the age of 6 and worsens [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2152,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_gspb_post_css":"","_uag_custom_page_level_css":"","advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[28],"tags":[],"class_list":["post-2149","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news_tnmu-en"],"author_meta":{"display_name":"admin","author_link":"https:\/\/www.tdmu.edu.ua\/science\/author\/admin\/"},"featured_img":"https:\/\/www.tdmu.edu.ua\/science\/wp-content\/uploads\/sites\/19\/2022\/09\/unnamed.jpg","uagb_featured_image_src":{"full":["https:\/\/www.tdmu.edu.ua\/science\/wp-content\/uploads\/sites\/19\/2022\/09\/unnamed.jpg",300,150,false],"thumbnail":["https:\/\/www.tdmu.edu.ua\/science\/wp-content\/uploads\/sites\/19\/2022\/09\/unnamed-150x150.jpg",150,150,true],"medium":["https:\/\/www.tdmu.edu.ua\/science\/wp-content\/uploads\/sites\/19\/2022\/09\/unnamed.jpg",300,150,false],"medium_large":["https:\/\/www.tdmu.edu.ua\/science\/wp-content\/uploads\/sites\/19\/2022\/09\/unnamed.jpg",300,150,false],"large":["https:\/\/www.tdmu.edu.ua\/science\/wp-content\/uploads\/sites\/19\/2022\/09\/unnamed.jpg",300,150,false],"1536x1536":["https:\/\/www.tdmu.edu.ua\/science\/wp-content\/uploads\/sites\/19\/2022\/09\/unnamed.jpg",300,150,false],"2048x2048":["https:\/\/www.tdmu.edu.ua\/science\/wp-content\/uploads\/sites\/19\/2022\/09\/unnamed.jpg",300,150,false]},"uagb_author_info":{"display_name":"admin","author_link":"https:\/\/www.tdmu.edu.ua\/science\/author\/admin\/"},"uagb_comment_info":0,"uagb_excerpt":"Myopia, also known as nearsightedness, is a common vision condition in which objects far away appear blurry. Myopia occurs when the shape of your eye causes light rays to refract incorrectly, resulting in out of focus images.&nbsp; Nearsightedness often begins in childhood and adolescence. It typically occurs first around the age of 6 and worsens&hellip;","coauthors":[],"tax_additional":{"categories":{"linked":["<a href=\"https:\/\/www.tdmu.edu.ua\/science\/en\/category\/news_tnmu-en\/\" class=\"advgb-post-tax-term\">News TNMU<\/a>"],"unlinked":["<span class=\"advgb-post-tax-term\">News TNMU<\/span>"]}},"comment_count":0,"relative_dates":{"created":"Posted 4 \u0440\u043e\u043a\u0438 ago","modified":"Updated 4 \u0440\u043e\u043a\u0438 ago"},"absolute_dates":{"created":"Posted on 02.09.2022","modified":"Updated on 02.09.2022"},"absolute_dates_time":{"created":"Posted on 02.09.2022 11:17","modified":"Updated on 02.09.2022 11:17"},"featured_img_caption":"","series_order":"","_links":{"self":[{"href":"https:\/\/www.tdmu.edu.ua\/science\/wp-json\/wp\/v2\/posts\/2149","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tdmu.edu.ua\/science\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.tdmu.edu.ua\/science\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.tdmu.edu.ua\/science\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tdmu.edu.ua\/science\/wp-json\/wp\/v2\/comments?post=2149"}],"version-history":[{"count":0,"href":"https:\/\/www.tdmu.edu.ua\/science\/wp-json\/wp\/v2\/posts\/2149\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.tdmu.edu.ua\/science\/wp-json\/wp\/v2\/media\/2152"}],"wp:attachment":[{"href":"https:\/\/www.tdmu.edu.ua\/science\/wp-json\/wp\/v2\/media?parent=2149"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.tdmu.edu.ua\/science\/wp-json\/wp\/v2\/categories?post=2149"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.tdmu.edu.ua\/science\/wp-json\/wp\/v2\/tags?post=2149"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}