Anaïs Makos and Oksana Kehoe Presented Findings from the Study “Biomarkers for Predicting Therapy Response in Psoriatic Arthritis”

On November 12, 2024, Anaïs Makos, a doctoral researcher working under the supervision of Oksana Kehoe at Keele University’s School of Medicine in the United Kingdom, delivered an online lecture, “Biomarkers for Predicting Response to Tumor Necrosis Factor Inhibitor Therapy in Patients with Psoriatic Arthritis.” This session was the second in a series of presentations by Keele University researchers, following an earlier lecture on osteoporosis by Zoe Paskins.

During her talk, Anaïs thoroughly discussed the main aspects of her research. She described psoriatic arthritis as a chronic inflammatory disease often accompanied by comorbidities such as obesity, diabetes, metabolic syndrome, and hypertension. She highlighted the diagnostic challenges of the disease’s diverse symptoms and explored modern treatment approaches, including biological therapies.

Her literature review identified promising biomarkers that could have predictive value in selecting effective therapies. These biomarkers included Th17 cells, Transmembrane TNF (tmTNF), Human serum albumin (HSA), FcRn receptor, Calprotectin, HMGB1 protein, Advanced glycation end-products (AGEs), Lymphotoxin-α (LTa),

The session, moderated by Professor Roman Komorovskyi, attracted postgraduate students, undergraduates, and faculty members who actively participated in a concise yet insightful discussion. Anaïs Makos’s presentation exemplified high-quality scientific research and effective communication of findings.